SPRING has arrived. Pioneering a new era of human health.
SPRING FORWARD
SPRING is a transformational platform technology that enables non-viral DNA delivery while precisely regulating gene expression in a cell-type specific way. SPRING is programmable, modular, redosable, stable and sustained.
- S — Sustained, long-lasting expression and scalable manufacturing
- P — Precise, cell-type specific gene expression
- R — Redosable
- I — Intra-nuclear, efficient targeting
- N — Non-integrating, non-triggering innate immunity
- G — Gene cargo of any size
UNIQUE ADVANTAGES OF SPRING
SPRING 's unique advantages make it a superior modality for developing a new class of medicine.
THE FUTURE IS SPRING
The SPRING platform has vast potential to transform human health.
The SPRING platform can generate an unlimited number of medicines, and is capable of being delivered through multiple routes of administration, such as topical, intra-muscular and intravenous, allowing for multiple use cases.
THERAPEUTIC AREAS
Genetic Diseases
Metabolic Diseases
Hematology
Oncology
Women’s Health
Immunology
Gastroenterology
Ophthalmology
Dermatology
USE CASES
Gene Therapy
Genetic Vaccination
Gene Editing
Diagnostics
We are ahead of the field and positioned to accelerate the advancement of our platform.
Manufacturability and scalability
We have developed a reliable, scalable manufacturing process that is fully enzymatic and low cost compared to viral and RNA-based manufacturing approaches. Production, including purificaiton, can take place in a single day. Our process can be decentralized in small-footprints or giga-scaled. We use natural, unmodified nucleotides that are abundantly available. Our platform technology is protected by a comprehensive IP portfolio.